Dehydration is one of the most dangerous side effects of diarrhea. Rhabdomyolysis is treatable. Examples of heart problems include heart disease, such as heart failure, or a past heart attack. At least 700 medications can cause diarrhea as a side effect. Are you dealing with a rheumatoid arthritis (RA) flare? What is the latest research on the form of cancer Jimmy Carter has? Medicines that may cause diarrhea include antibiotics, antacids containing magnesium, and medicines used to treat cancer. Diarrhea often causes hemorrhoids to bleed due to the presence of digestive acid or bile in the loose stools. It goes away when the original infection does. If youre concerned about Plaquenil and weight gain or weight loss, talk with your doctor. The most common causes of acute and persistent diarrhea are infections, travelers diarrhea, and side effects of medicines. Stool color can be influenced by the color of the food you eat. One source estimates that approximately 3040% of people have trouble absorbing significant amounts of fructose. Chronic diarrhea is classified as fatty or malabsorption, inflammatory or most commonly watery. This can help to avoid a recurrence of diarrhea. You can learn more about how we ensure our content is accurate and current by reading our. And it usually goes away when the statin is stopped. However, this common household ingredient is highly, This article looks at some possible natural alternatives to laxatives for people looking to have a bowel movement. Thats because Plaquenil doesnt cure these conditions, it only reduces their symptoms. If you use medications regularly, ask your doctor whether any of them might be causing your diarrhea. Sometimes, it turns out to be something you're eating or a medication you're taking. A wide range of diseases can cause it. Its not known whether Lipitor passes into breast milk. Taking Lipitor within 6 months of having a stroke or transient ischemic attack (TIA) can increase your risk of hemorrhagic stroke. Soluble fibers attract water during digestion and form gels. Diabetes can cause diarrhea, along with several other gastrointestinal (digestive) problems. Plaquenil may not be right for you if you have certain medical conditions or other factors that affect your health. Plaquenil may also cause serious skin-related side effects. We also look at when to see a, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. 0,00 . Changing your diet. Its not uncommon for many people to have diarrhea several times a year. It is typically a sign of infection or dysbiosis in the hindgut. Check out our top seven picks to find one that's right for you. Electrolyte losses can have serious consequences. This is usually temporary and it means that you need to avoid items with lactose (dairy products) until your diarrhea is gone. Infections by other organisms and pre-formed toxins. It normally lasts 2 to 3 days. They can also use this device to take a small sample of tissue. You need to drink plenty of fluids to replace whats lost. If you have certain types of arthritis, lupus, or malaria, your doctor might suggest Plaquenil as a treatment for your condition. In extreme cases of diarrhea, you can become very dehydrated and this can lead to serious complications. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. In either case, dont ignore this symptom. Antibiotics can change the balance of bacteria normally found in the intestines, allowing certain types of bacteria like C. difficile to thrive. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, drinks that contain electrolytes, such as sports drinks. Some people with lactose intolerance may tolerate small amounts of dairy products that are aged or lower in lactose. Taking two tablespoons of Kaopectate or two tablespoons of Pepto-Bismol after each loose stool. If so, ask if you can try an alternative or try going off of it temporarily. Get useful, helpful and relevant health + wellness information. Content produced by the NIDDK is carefully reviewed by NIDDK scientists and other experts. In this article, we will look at the effects of cholesterol on the body and how to lower the, High cholesterol is a risk factor for heart attacks and coronary heart disease, because it builds up in the arteries, narrowing them. Best food forward: Are algae the future of sustainable nutrition? Its not known if taking Plaquenil long term raises your risk of other side effects. Medicines that must be taken for a long time may cause chronic diarrhea. Always check with your provider before giving your child a new liquid or treatment of any kind. Advertising on our site helps support our mission. No, there arent any side effects that are specific to people taking Plaquenil for lupus. Plaquenil can damage your retina, which may lead to permanent loss of vision. However, the food a person eats can sometimes cause diarrhea and related symptoms. Chronic Diarrhea: Diagnosis and Management. Diarrhea is defined as the excessive and frequent defection of loose or liquid stool. Dehydration and malabsorption can be serious complications of diarrhea. Avoiding foods high in capsaicin may help reduce symptoms and frequency of diarrhea. If youd like to notify the FDA about a side effect youve had with Plaquenil, visit MedWatch. It normally lasts 2 to 3 days. But it could cause serious side effects in a breastfed child if it does. Dizziness, cough, hair loss, and memory loss werent reported by people taking Lipitor in clinical trials. headache. Theres no cure for rheumatoid arthritis, but early treatment can manage the condition and keep you active. A tip for managing diarrhea in an adult with over-the-counter medication includes: When you have an acute case of diarrhea, you can often take care of it without needing any medication. Dizziness can also be a symptom of some serious side effects of Plaquenil, such as low blood sugar and heart problems. If you have a heart problem, ask your doctor if Plaquenil is safe for you. Last medically reviewed on April 25, 2022, Eating a bland diet can help a person reduce the symptoms of diarrhea and speed their recovery. (With myopathy, you have muscle pain and weakness.) Cleveland Clinic Children's is dedicated to the medical, surgical and rehabilitative care of infants, children and adolescents. And doctors often prescribe folic acid with methotrexate to help reduce its side effects. Its common and usually not serious. In people with intolerances, gluten and lactose may also cause diarrhea. Inflammatory diarrhea tends to come out more frequently and in smaller amounts. You should have an eye exam within 1 year of starting treatment with Plaquenil. Symptoms of serious skin-related side effects include: While taking Plaquenil, its important to protect your skin from UV light to avoid getting a sunburn. Sip small amounts of fluids often.Liquid probiotics may also help. Spicy foods containing hot peppers are another cause of diarrhea. can plaque off cause diarrhea. When diarrhea lasts for a long period of time (several weeks), your healthcare provider will base your treatment on the cause. You may need treatment that targets your chronic diarrhea separately. (Plaquenil is also available as the generic drug hydroxychloroquine.) If you have G6PD deficiency, talk with your doctor about whether Plaquenil is safe for you. Lipitors side effects dont vary based on the strength of the drug. This may increase your risk of side effects. The list below includes factors to consider. Lipitor can cause certain side effects, some of which are more common than others. But its not known how often these side effects occur. This list doesnt include all possible mild side effects of the drug. See this article for other at-home remedies you can try to ease your upset stomach. Diarrhea often means frequent trips to the bathroom. It's more common in people who have had diabetes for a long time. Many diseases can cause chronic diarrhea. They can help you decide if Plaquenil is a good treatment option for you. Your side effect notes can include things such as: Keeping notes and sharing them with your doctor will help your doctor learn more about how Plaquenil affects you. These can be warning signs of things like: Also, call your doctor right away if you have diarrhea and any of thesesigns of dehydration: Your doctor will ask about your medical history and what medications you take, as well as what youve eaten or had to drink recently. Heavy alcohol consumption can cause liver damage, which is a possible side effect of Lipitor. All rights reserved. Gastroenteritis can be caused by: a virus - such as norovirus or rotavirus bacteria - such as campylobacter and Escherichia (E. coli), which are often picked up from contaminated food This could involve a few different treatment options, including: How should I take over-the-counter medications for diarrhea? If you eat or drink excessive amounts of them on a regular basis, or if youre particularly sensitive to any of them, they might cause chronic diarrhea. More serious symptoms of diarrhea include: If you have watery stools more than three times a day and you're not drinking enough fluids, you could become dehydrated. Some people get it more often. Your body doesnt become dependent on Plaquenil during treatment. But if you have a raised risk of retinal damage, these exams are recommended every year. Aggravating factors include stress, poor diet, and nonsteroidal anti-inflammatory drugs such as ibuprofen and aspirin. If you have any concerns, its always best to call your healthcare provider. There isnt a direct interaction between consuming alcohol and taking Lipitor. G6PD is a protein that helps red blood cells work correctly. They can suggest ways to help you reach or maintain a moderate body weight. And be sure to get up slowly. An allergic reaction is possible after taking Plaquenil. A strong and urgent need to have a bowel movement. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation, mask requirements and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. Isolating the offending food or drink and reducing it or eliminating it from your diet may solve the problem. What could be the cause of morning diarrhea? Several things you can do to care for diarrhea include: Sometimes, diarrhea can also make you lactose intolerant. McRorie, JR., J. W. (2015). Read on to learn about potential common, mild, and serious side effects. Water alone doesnt contain electrolytes. * Sex and gender exist on spectrums. These symptoms can include: The cause of most self-limited diarrhea is generally not identified. While foods high in insoluble fiber can worsen diarrhea, foods containing soluble fiber can help promote more formed stools, reducing diarrhea. Antibiotic-associated diarrhea can begin any time while youre taking the antibiotic or shortly thereafter. Kidney or liver problems can raise your risk of side effects with Plaquenil. But Crestor is more likely to cause constipation. Instead of drinking liquids with your meals, drink liquids between meals. Will Plaquenil affect my ability to drive. If you drink alcohol, talk with your doctor about how much is safe for you to consume while youre taking Plaquenil. Many people may be gluten intolerant to varying degrees. However, if you have symptoms of a serious skin-related side effect, contact your doctor right away. Something is making it hard for your colon to absorb water as it normally would, or making it excrete extra water, or both. Find the latest information from the globally recognized leader in digestive diagnosis, treatments and surgical innovations. To see a list of how often certain side effects were reported based on the dose of Lipitor people took, view Lipitors patient information. You may also try using a. Some infections from bacteria and parasites that cause diarrhea do not go away quickly without treatment. Your doctor can give further advice on what to do. We do not endorse non-Cleveland Clinic products or services. The color of your poop (stool) can vary. Categories . However, if youre breastfeeding or plan to breastfeed, talk with your doctor about the best way to feed your child while taking Plaquenil. It can affect your confidence, as well as your overall quality of life. Theyll have you stop taking the drug. By using an over-the-counter product like bismuth subsalicylate (Pepto-Bismol or Kaopectate) youll usually feel better very quickly. It can lead to problems with your kidneys, including kidney failure. Your body loses water each time you have diarrhea. Some infections, food allergies and intolerances, digestive tract problems, abdominal surgery, and long-term use of medicines can cause chronic diarrhea. All rights reserved. They can advise you on how much, if any, is safe for you to drink while youre taking Lipitor. You should drink at least six 8-ounce glasses of fluids each day. The most thorough and safe way to scrape plaque off the dog's teeth is with a professional dental cleaning. People with untreated hypothyroidism may have a higher risk of myopathy with Lipitor. Fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) are a category of carbohydrates. Yes, diarrhea can cause hemorrhoids to bleed, as can straining during a bowel movement or sitting for an extended period of time. Are side effects less common when Plaquenil is taken to help prevent. This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases Although its not common, abnormal liver function is a possible serious side effect of Lipitor. Dehydration is a dangerous side effect of diarrhea. In the very young (infants and small children) and the very old, this can have serious consequences. Dairy and gluten may also cause diarrhea in those with intolerances. For information about how to prepare, advice on prevention and treatment, and expert recommendations, visit our coronavirus hub. Allergies and intolerances to certain foods (. Talk with your doctor about your health history before you take Plaquenil. Kidney or liver problems. Abdominal surgery is an operation on the appendix, gallbladder, large intestine, liver, pancreas, small intestine, spleen, or stomach. If your doctor diagnoses a serious skin reaction from Plaquenil, youll need to stop taking the medication. However, some side effects happen more or less often depending on its strength. Your doctor will have you stop taking Lipitor if they confirm you have myopathy as a side effect. There are many home remedies and over-the-counter medications that can reduce symptoms. In addition, Plaquenil can also make liver problems worse. If you take Plaquenil for lupus or rheumatoid arthritis, you may notice that stopping treatment makes your condition get worse. If your diarrhea is caused by an infection or parasite, youll need to see a healthcare provider for treatment. Small amounts of Plaquenil can get into breast milk. Also talk with them about any medications you take. Problems digesting carbohydrates or proteins can prolong diarrhea. In these situations, there are a few diagnostic tests that your provider may order. If you and your doctor agree that Lipitor is working for you, youll likely take it long term. (https://pubmed.ncbi.nlm.nih.gov/32293842/), (https://iffgd.org/gi-disorders/diarrhea/common-causes/). You should not take Lipitor while pregnant or breastfeeding. This helps your doctor notice abnormal liver function before it becomes serious. What should I do if Plaquenil upsets my stomach? Can you remove dog tartar at home? You should always consult your doctor or another healthcare professional before taking any medication. Make sure to hydrate throughout day. So if you stop treatment, this can make your symptoms come back. You also need to stay hydrated. This is called photosensitivity, and it can increase your risk of getting a sunburn. If youre pregnant or plan to become pregnant, talk with your doctor about the possible risks and benefits of taking Plaquenil. Plaquenil can also cause blind spots in your vision. If you experience cramping in your stomach with diarrhea, it could help to cut back on things that cause gas. Some people may experience mild or serious side effects during Plaquenil treatment. The American College of Gastroenterology recommends seeing a doctor if diarrhea continues for longer than 48 hours. Some possible causes of diarrhea include food poisoning, infections, food allergies or intolerances, and medication. Diarrhea may also signal a more serious problem. Get useful, helpful and relevant health + wellness information. Its not known how often eye-related side effects happen with Plaquenil, but the drug can sometimes cause such side effects. You actually can help your diarrhea by changing your diet. These are side effects that last for a long time or are permanent. Some people get it more often. Caffeine is a stimulant and accelerates the rate that food moves through the intestines. The provider will thoroughly examine the possible causes of your chronic diarrhea in order to identify the right treatment. Is the ketogenic diet right for autoimmune conditions? It is a potent chemical that can irritate the lining of the stomach and intestines. Food allergies and intolerances Allergies to foods such as cow's milk, soy, cereal grains, eggs, and seafood may cause chronic diarrhea. nausea and vomiting. Doing a stool test on a collected stool sample to check for blood, bacterial infections, parasite and inflammatory markers. Sometimes, people with diabetes-related diarrhea also experience fecal (bowel) incontinence, especially at night. But its not known how often this occurs. Your doctor can recommend safer treatments for your condition if you have liver problems. These factors can all cause or worsen diarrhea. Can poor sleep impact your weight loss goals? The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. This article explores the foods that cause diarrhea, how to tell if diarrhea is due to something that has been eaten, treatment options, and when to see a doctor. 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event, (https://www.niddk.nih.gov/health-information/digestive-diseases/diarrhea), (https://www.cdc.gov/healthywater/pdf/global/programs/globaldiarrhea508c.pdf), (https://www.merckmanuals.com/professional/gastrointestinal-disorders/symptoms-of-gastrointestinal-disorders/diarrhea), Visitation, mask requirements and COVID-19 information. Patting your rectal area dry with a clean soft towel after getting out of the tub or shower. Its important to note that muscle pain or weakness may be a sign of more serious side effects. Plaque off and diarrhoea Lucy had diarrhoea for a few days and the only thing that had changed was trying plaque off. Use sunscreen on skin thats not covered. However, since the drug was approved, there have been a few studies looking at statins, including Lipitor. Some people have chronic bowel diseases that cause chronic diarrhea. Capsaicin is the compound that makes chili peppers taste spicy. Common causes can include dairy, spicy food, and greasy food. These side effects may be temporary, lasting a few days or weeks. Chronic diarrhea means having loose stools regularly for more than four weeks. An estimated 1% to 3% of the population has chronic diarrhea. And theyll discuss other treatment options with you. Here are some frequently asked questions about the drugs side effects and their answers. queensland figure skating. Categories . 28 de mayo de 2018. High doses of bismuth subsalicylate with Plaquenil can increase your risk of low blood sugar. Some foods are difficult to digest, increase water levels in the bowel, and irritate the digestive system lining. Plaquenil can cause heart-related side effects. WebMD does not provide medical advice, diagnosis or treatment. They can review with you the risks and benefits of this drug. If you have any questions or concerns about your childs diarrhea, dont hesitate to call your provider. 2005-2023 Healthline Media a Red Ventures Company. Your healthcare provider can help. Some people may have hair loss while taking Plaquenil. Recent stroke or transient ischemic attack (TIA). Several types of bacteria can enter your body through contaminated food or water and cause diarrhea. Some that can cause chronic diarrhea include: Healthcare providers sometimes classify diarrhea into three or four types as a way of narrowing down the cause. Infections lasting more than 2 weeks and less than 4 weeks can cause persistent diarrhea. If you have it for more than 3 days, make an appointment. Ask your doctor what other medications are better options for you. Common bacteria that cause diarrhea include Campylobacter, Escherichia coli (E. coli), Salmonella, and Shigella. Plaquenil may cause a skin rash or itching. However, a few other examples include: A low FODMAP diet can be challenging due to its various food restrictions. You may also feel bloated, have lower abdominal cramping and sometimes experience nausea. Published by at 16 de junio de 2022. Fatty diarrhea may be less frequent but with greater volume. And your doctor may switch you to a different treatment for your condition. For diarrhea, it may help to eat foods that are low in fiber and bland, such as bananas or white rice. Learn more about some of the side effects that Lipitor may cause. Learn more about gluten intolerance here. (NIDDK), part of the National Institutes of Health. If youd like to learn more about Lipitor and its side effects, talk with your doctor or pharmacist. Home; Products; About Us. Diarrhea can happen for a wide variety of reasons and it usually goes away on its own in one to three days. Treating the underlying condition may solve your chronic diarrhea, or the condition may not be directly treatable. Its important to always follow the instructions on the packaging when you take an over-the-counter medication for diarrhea. Electrolyte drinks (Pedialyte) for older children this is not recommended for babies. Over-the-counter (OTC) medications may also help decrease these symptoms. No, its not likely. Many viruses cause diarrhea, including norovirus and rotavirus. Diarrhea is a bowel disorder that occurs with frequent (more than three per day) discharges of liquid or semi-liquid stools; it is a symptom and not a disease. Serious side effects that have been reported with Plaquenil include: * To learn more about this side effect, see the Side effects explained section below. If you have any changes in your vision while taking Plaquenil or after stopping treatment, talk with your doctor right away. Many people get diarrhea a few times a year. Lactose intolerance is a common condition that may cause diarrhea after eating foods or drinking liquids that contain milk or milk products. Drinks and foods that contain caffeine can cause diarrhea and loose stools in some people. Plaquenil can sometimes cause seizures or problems with movement, such as tremors or twitching.If you have a neurological disorder (a condition affecting your brain and nerves), taking Plaquenil could worsen the symptoms of your condition. But if you take Plaquenil to treat or help prevent malaria, you shouldnt notice any problems after stopping treatment. Plaquenil is a tablet that you take by mouth. If you still have diarrhea after 4 weeks, then you have chronic diarrhea. Dark urine and small amounts of urine or loss of urine production. Sugar alcohols such as sorbitol, mannitol, and xylitol may cause diarrhea in some people. Like most drugs, Plaquenil can cause an allergic reaction in some people. (https://pubmed.ncbi.nlm.nih.gov/27496381/), Visitation, mask requirements and COVID-19 information, Small intestinal bacterial overgrowth (SIBO). The three main types are inflammatory, fatty and watery. Sometimes, it turns out to be something youre eating or a medication youre taking. Learn about treatments and strategies that can help you navigate through them. If you experience nausea or vomiting while taking Plaquenil, try eating smaller meals or plain foods, or drinking cold liquids. For more information on how to treat or help prevent an upset stomach, talk with your doctor or pharmacist. Diarrhea is a common problem in horses as it can be a result of many different causes. Examples of some questions you might want to ask your doctor include: If you have rheumatoid arthritis (RA) and want tips for managing your condition and more, sign up for Healthlines RA newsletter. Some divide watery diarrhea into two sub-types (secretory and osmotic) to make four main types. It is important to look out for signs of dehydration in these groups, such as: DIarrhea can be difficult to diagnose in the absence of an underlying cause. Normally, your colon receives liquefied food waste from your small intestine and gradually condenses it into solid poop. While taking Plaquenil, contact your doctor right away if you have any symptoms of heart-related side effects. For relief, take a warm bath or sitz bath. Drinking alcohol with Plaquenil could raise your risk of certain side effects. Your doctor can help determine whether treatment with Lipitor is safe for you. Your doctor can help determine whether treatment with Lipitor is safe for you. If you have blurry vision or eye-related side effects while youre taking Lipitor, talk with your doctor or pharmacist. Like many other drugs, Lipitor can cause side effects ranging from mild to serious. Make sure you stay hydrated while you have diarrhea. Infections in the digestive tract that spread through foods or drinks are called foodborne illnesses. In most cases, diarrhea is caused by a virus or bacteria that your body is trying to flush out. Call your healthcare provider if you have diarrhea that fails to get better or go away, or if you experience symptoms of dehydration. If you have diarrhea that fails to improve or resolve completely, you should call your healthcare provider. Other causes are often curable with the right treatment. Cardiovascular health: Insomnia linked to greater risk of heart attack. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. If your diarrhea is hanging on and not resolving, take a look at your medications. Diarrhea can cause dehydration (when your body loses large amounts of water), electrolyte imbalance (loss of sodium, potassium and magnesium that play a key role in vital bodily functions) and kidney failure (not enough blood/fluid is supplied to the kidneys). Chloroquine or hydroxychloroquine and/or azithromycin. But Crestor is more likely to cause constipation. Fructose is a component of table sugar and occurs naturally in fruits. Serious side effects that have been reported and their symptoms include: * For more information on this side effect, see Side effect specifics below. Find the latest information from the globally recognized leader in digestive diagnosis, treatments and surgical innovations. Also, be sure to let your doctor know about your diarrhea if you havecancer, or have had recent treatment for it. Keep a record of any bowel movements that: For the majority of mild diarrhea cases, you wont need medical attention. Cardiovascular health: Insomnia linked to greater risk of heart attack. These can include beans, cabbage, Brussels sprouts, beer and carbonated beverages. Advertising on our site helps support our mission. Learn more about some of the side effects Plaquenil may cause. This may help to identify links between certain foods and diarrhea symptoms. More serious cases of diarrhea may require medical attention. All rights reserved. To figure out the cause, your doctor will want to know your symptoms and medical history. Their symptoms in adults, infants, toddlers, and young children are as follows. People that do not have celiac disease may still have issues tolerating gluten. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Over-the-counter medications can be dangerous in young children and all treatments of diarrhea in children should be guided by their healthcare provider. However, both alcohol and Lipitor can cause liver damage. If you experience any symptoms of liver problems while youre taking Lipitor, call your doctor right away. Diarrhea can be watery, fatty or inflammatory. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, https://www.nhs.uk/conditions/antibiotics/side-effects/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944381, https://www.ncbi.nlm.nih.gov/books/NBK459168, https://iffgd.org/gi-disorders/diarrhea/common-causes, https://www.mdpi.com/2072-6643/11/3/551/htm, https://www.nhs.uk/conditions/diarrhoea-and-vomiting/, https://www.niddk.nih.gov/health-information/digestive-diseases/diarrhea/eating-diet-nutrition, https://onlinelibrary.wiley.com/doi/10.1111/jgh.15410, https://www.nhs.uk/conditions/lactose-intolerance/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093271, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415970/, https://www.nhs.uk/conditions/coeliac-disease/, https://www.nhs.uk/conditions/probiotics/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915127/, https://www.health.nsw.gov.au/heal/factsheets/sweeteners.pdf, https://aboutibs.org/treatment-main/low-fodmap-diet.html, https://www.niddk.nih.gov/health-information/digestive-diseases/diarrhea/treatment. A general rule is not to use over-the-counter medications for diarrhea if you also have a fever or blood in your stool. Yes, Plaquenil can cause some long-term side effects. However, it is most prevalent in the Middle East, Southeast Asia, and Sub-Saharan African communities. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication.